Off the coast of the volcanic island of Santorini, the intrepid archaeologist Lara Croft makes the unexpected discovery of a pulsating golden orb able to guide its holder to the mythical Pandora's Box. As the legendary artifact contains ancient mysteries of unfathomable power - said to contain one of the deadliest plagues on Earth, Lara is tasked by MI6 to make sure it doesn't fall into the wrong hands. With the aid of former Marine turned mercenary Terry Sheridan, she travels the world in pursuit of the precious item in a race against time; she must beat the unscrupulous Nobel Prize-winning scientist turned bioterrorist, Jonathan Reiss, to it.
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| Directing | Jan de Bont | Director |
| Writing | Dean Georgaris | Screenplay |
| Production | Lawrence Gordon | Producer |
| Production | Lloyd Levin | Producer |
| Sound | Alan Silvestri | Original Music Composer |
| Editing | Michael Kahn | Editor |
| Art | Sonja Klaus | Set Decoration |
| Production | Dan Hubbard | Casting |
| Production | John Hubbard | Casting |
| Sound | John Hughes | Sound |
| Visual Effects | Ferran Domenech | Character Modelling Supervisor |
| Visual Effects | Ben Shepherd | Effects Supervisor |
| Sound | Peter Afterman | Music Supervisor |
| Visual Effects | Chris Corbould | Special Effects Supervisor |
| Visual Effects | Steven Begg | Visual Effects Supervisor |
| Crew | Simon Crane | Stunt Coordinator |
| Costume & Make-Up | Lindy Hemming | Costume Designer |
| Production | Kirk M. Petruccelli | Production Designer |
| Writing | James V. Hart | Story |
| Writing | Steven E. de Souza | Story |
| Production | Jeremy Heath-Smith | Executive Producer |
| Production | Philip Lee | Line Producer |
| Crew | David Tattersall | Cinematography |
| Crew | John Slattery | Compositor |
| Crew | Jo McLaren | Stunts |
| Camera | David Tattersall | Director of Photography |
| Art | Dennis Bosher | Art Direction |
| Art | Silver Cheung | Art Direction |
| Art | John Fenner | Art Direction |
| Art | John C. Hill | Art Direction |
| Art | Paul Kirby | Art Direction |
| Art | Frank Walsh | Art Direction |
| Sound | Steve Boeddeker | Supervising Sound Editor |
| Production | Shelly Clippard | Associate Producer |
| Production | Holly Goline | Associate Producer |
| Production | Louis A. Stroller | Co-Producer |
| Costume & Make-Up | Suzanne Belcher | Assistant Makeup Artist |
| Costume & Make-Up | Darlene Forrester | Hairdresser |
| Costume & Make-Up | Richard Glass | Contact Lens Technician |
| Costume & Make-Up | Frances Hannon | Makeup Department Head |
| Costume & Make-Up | Belinda Hodgson | Makeup Artist |
| Costume & Make-Up | Jan Jamison | Hairstylist |
| Costume & Make-Up | Colin Jamison | Hairstylist |
| Costume & Make-Up | Tracey Lee | Makeup Artist |
| Art | Neil Morrill | Sculptor |
| Costume & Make-Up | Belinda Parish | Makeup Artist |
| Costume & Make-Up | Janeen Schreyer | Makeup Designer |
| Costume & Make-Up | Jemma Scott-Knox-Gore | Contact Lens Technician |
| Costume & Make-Up | Lisa Tomblin | Hairstylist |
| Costume & Make-Up | Shaunna Harrison | Makeup Artist |
| Production | Pawel Araskiewicz | Production Assistant |
| Production | Terry Bamber | Production Manager |
| Production | Erica Bensly | Production Manager |
| Production | Chris Brock | Production Manager |
| Production | Chu Chen-On | Production Manager |
| Production | Peter Heslop | Unit Production Manager |
| Production | Jeremy Johns | Production Manager |
| Production | Tim Lewis | Unit Manager |
| Production | Jenny Panoutsopoulos | Production Manager |
| Production | Jacob Peratrovich | Assistant Unit Manager |
| Production | Cindy Rodkin | Production Supervisor |
| Crew | Michael Solinger | Post Production Supervisor |
| Production | Johnny Wang Yin-Ming | Production Supervisor |
| Directing | Pierros Andrakakos | Second Second Assistant Director |
| Directing | Dimitris Birbilis | Second Assistant Director |
| Directing | Rob Burgess | Third Assistant Director |
| Directing | Josephine Chan | Second Assistant Director |
| Directing | Wai Pun Chan | Second Assistant Director |
| Directing | Thomas Chow Wai-Kwan | First Assistant Director |
| Directing | Simon Crane | Second Unit Director |
| Directing | Amy Gilliam | Assistant Director |
| Directing | Barbara Efthymiou Harris | Third Assistant Director |
| Directing | Toby Hefferman | Second Assistant Director |
| Directing | Martin Krauka | Second Second Assistant Director |
| Directing | Ben Lanning | Third Assistant Director |
| Directing | Cliff Lanning | First Assistant Director |
| Directing | Iain Lawrence | Assistant Director |
| Directing | Terence Madden | Third Assistant Director |
| Directing | Terry Madden | First Assistant Director |
| Directing | Okongo Mbanda | Third Assistant Director |
| Directing | Bob Nyanja | Third Assistant Director |
| Directing | Tony Rimwah | Third Assistant Director |
| Directing | Matthew Sharp | Second Assistant Director |
| Directing | Sin Ka-Leung | Second Second Assistant Director |
| Directing | Matthew Tang Hon-Keung | First Assistant Director |
| Art | Dominic Ackland-Snow | Supervising Carpenter |
| Art | Christopher Arnold | Props |
| Art | Christopher Arnold | Set Dresser |
| Art | Ravi Bansal | Conceptual Illustrator |
| Art | Andrew Barnden | Storyboard Artist |
| Art | Rob Bean | Sculptor |
| Art | Rob Bliss | Conceptual Illustrator |
| Art | Guy Bradley | Draughtsman |
| Art | Mike Britton | Assistant Set Decoration |
| Art | Adam Brockbank | Conceptual Illustrator |
| Art | Mark Buck | Other |
| Art | Neal Callow | Draughtsman |
| Art | Anthony Caron-Delion | Assistant Art Director |
| Art | Paul Carling | Conceptual Illustrator |
| Art | Mick Chubbock | Other |
| Art | Andrew David Clark | Graphic Designer |
| Art | Chris Clarke | Props |
| Crew | Rowley Irlam | Stunts |
| Costume & Make-Up | Dan Grace | Wardrobe Supervisor |
| Visual Effects | Mark Bakowski | Digital Compositor |
| Crew | Diane Kingston | Digital Effects Producer |
| Visual Effects | Phillip Leonhardt | Compositing Artist |
| Editing | Jabez Olssen | Assistant Editor |
