Lara Croft is tasked by MI6 to find the mythological Pandora's Box, an object from ancient legends which supposedly contains one of the deadliest plagues on Earth, before evil Nobel Prize-winning scientist turned bioterrorist Jonathan Reiss can get his hands on it. Lara ventures to an underwater temple in search of a magical luminous orb, the key to finding Pandora's Box, but after securing it, it is promptly stolen by the villainous leader of a Chinese crime syndicate who in turn plans to sell the orb to Reiss. Lara must recover the box before evil mastermind Reiss uses it to construct a weapon of catastrophic capabilities.
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| Sound | Alan Silvestri | Original Music Composer |
| Editing | Michael Kahn | Editor |
| Production | Philip Lee | Line Producer |
| Production | Lawrence Gordon | Producer |
| Production | John Hubbard | Casting |
| Writing | Steven E. de Souza | Story |
| Production | Lloyd Levin | Producer |
| Directing | Jan de Bont | Director |
| Production | Dan Hubbard | Casting |
| Camera | David Tattersall | Director of Photography |
| Crew | David Tattersall | Cinematography |
| Writing | James V. Hart | Story |
| Sound | Steve Boeddeker | Supervising Sound Editor |
| Costume & Make-Up | Lindy Hemming | Costume Designer |
| Art | John Fenner | Art Direction |
| Art | Dennis Bosher | Art Direction |
| Production | Tim Lewis | Unit Manager |
| Art | Chris Clarke | Props |
| Production | Kirk M. Petruccelli | Production Designer |
| Art | Sonja Klaus | Set Decoration |
| Writing | Dean Georgaris | Screenplay |
| Art | Frank Walsh | Art Direction |
| Sound | Peter Afterman | Music Supervisor |
| Production | Louis A. Stroller | Co-Producer |
| Directing | Amy Gilliam | Assistant Director |
| Costume & Make-Up | Colin Jamison | Hairstylist |
| Costume & Make-Up | Lisa Tomblin | Hairstylist |
| Production | Chen On Chu | Production Manager |
| Crew | Michael Solinger | Post Production Supervisor |
| Crew | Simon Crane | Stunt Coordinator |
| Directing | Simon Crane | Second Unit Director |
| Art | Paul Kirby | Art Direction |
| Art | Neal Callow | Draughtsman |
| Production | Jeremy Heath-Smith | Executive Producer |
| Visual Effects | Chris Corbould | Special Effects Supervisor |
| Art | Silver Cheung | Art Direction |
| Directing | Matthew Tang | First Assistant Director |
| Directing | Bob Nyanja | Third Assistant Director |
| Costume & Make-Up | Janeen Schreyer | Makeup Designer |
| Directing | Tony Rimwah | Third Assistant Director |
| Art | Ravi Bansal | Conceptual Illustrator |
| Directing | Dimitris Birbilis | Second Assistant Director |
| Production | Peter Heslop | Unit Production Manager |
| Art | Anthony Caron-Delion | Assistant Art Director |
| Art | Guy Bradley | Draughtsman |
| Directing | Thomas Chow Wai-Kwan | First Assistant Director |
| Production | Chris Brock | Production Manager |
| Production | Jeremy Johns | Production Manager |
| Production | Johnny Wang Yin-Ming | Production Supervisor |
| Costume & Make-Up | Belinda Parish | Makeup Artist |
| Production | Shelly Clippard | Associate Producer |
| Art | Neil Morrill | Sculptor |
| Costume & Make-Up | Frances Hannon | Makeup Department Head |
| Production | Terry Bamber | Production Manager |
| Production | Holly Goline | Associate Producer |
| Art | Dominic Ackland-Snow | Supervising Carpenter |
| Production | Erica Bensly | Production Manager |
| Visual Effects | Steven Begg | Visual Effects Supervisor |
| Costume & Make-Up | Suzanne Belcher | Assistant Makeup Artist |
| Art | John C. Hill | Art Direction |
| Production | Jenny Panoutsopoulos | Production Manager |
| Crew | Jo McLaren | Stunts |
| Directing | Cliff Lanning | First Assistant Director |
| Directing | Terry Madden | First Assistant Director |
| Costume & Make-Up | Jan Jamison | Hairstylist |
| Directing | Toby Hefferman | Second Assistant Director |
| Art | Andrew David Clark | Graphic Designer |
| Production | Jacob Peratrovich | Assistant Unit Manager |
| Directing | Rob Burgess | Third Assistant Director |
| Directing | Martin Krauka | Second Second Assistant Director |
| Costume & Make-Up | Belinda Hodgson | Makeup Artist |
| Art | Adam Brockbank | Conceptual Illustrator |
| Costume & Make-Up | Richard Glass | Contact Lens Technician |
| Directing | Matthew Sharp | Second Assistant Director |
| Costume & Make-Up | Jemma Scott-Knox-Gore | Contact Lens Technician |
| Costume & Make-Up | Tracey Lee | Makeup Artist |
| Directing | Pierros Andrakakos | Second Second Assistant Director |
| Costume & Make-Up | Darlene Forrester | Hairdresser |
| Crew | John Slattery | Compositor |
| Directing | Terence Madden | Third Assistant Director |
| Art | Mike Britton | Assistant Set Decoration |
| Art | Rob Bliss | Conceptual Illustrator |
| Directing | Iain Lawrence | Assistant Director |
| Directing | Ben Lanning | Third Assistant Director |
| Art | Rob Bean | Sculptor |
| Art | Christopher Arnold | Set Dresser |
| Art | Christopher Arnold | Props |
| Costume & Make-Up | Shaunna Harrison | Makeup Artist |
| Production | Pawel Araskiewicz | Production Assistant |
| Production | Cindy Rodkin | Production Supervisor |
| Directing | Josephine Chan | Second Assistant Director |
| Directing | Wai Pun Chan | Second Assistant Director |
| Directing | Barbara Efthymiou Harris | Third Assistant Director |
| Directing | Okongo Mbanda | Third Assistant Director |
| Directing | Sin Ka-Leung | Second Second Assistant Director |
| Art | Andrew Barnden | Storyboard Artist |
| Art | Mark Buck | Other |
| Art | Paul Carling | Conceptual Illustrator |
| Art | Mick Chubbock | Other |
| Sound | John Hughes | Sound |
