Tasked by MI6 to find the mythological Pandora's Box, an ancient object supposedly containing one of the deadliest plagues on Earth, Lara Croft must beat evil Nobel Prize-winning scientist turned bioterrorist Jonathan Reiss to it.
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| Writing | Dean Georgaris | Screenplay |
| Production | Lloyd Levin | Producer |
| Production | Lawrence Gordon | Producer |
| Directing | Jan de Bont | Director |
| Art | Sonja Klaus | Set Decoration |
| Sound | Alan Silvestri | Original Music Composer |
| Editing | Michael Kahn | Editor |
| Production | John Hubbard | Casting |
| Production | Dan Hubbard | Casting |
| Writing | Steven E. de Souza | Story |
| Crew | David Tattersall | Cinematography |
| Production | Jeremy Heath-Smith | Executive Producer |
| Writing | James V. Hart | Story |
| Production | Philip Lee | Line Producer |
| Crew | John Slattery | Compositor |
| Crew | Jo McLaren | Stunts |
| Camera | David Tattersall | Director of Photography |
| Costume & Make-Up | Darlene Forrester | Hairdresser |
| Directing | Wai Pun Chan | Second Assistant Director |
| Directing | Sin Ka-Leung | Second Second Assistant Director |
| Art | Guy Bradley | Draughtsman |
| Art | Paul Kirby | Art Direction |
| Production | Pawel Araskiewicz | Production Assistant |
| Directing | Dimitris Birbilis | Second Assistant Director |
| Art | Neal Callow | Draughtsman |
| Art | Paul Carling | Conceptual Illustrator |
| Production | Chen On Chu | Production Manager |
| Directing | Okongo Mbanda | Third Assistant Director |
| Art | Ravi Bansal | Conceptual Illustrator |
| Art | Mike Britton | Assistant Set Decoration |
| Production | Chris Brock | Production Manager |
| Art | Adam Brockbank | Conceptual Illustrator |
| Art | Mick Chubbock | Other |
| Production | Louis A. Stroller | Co-Producer |
| Costume & Make-Up | Richard Glass | Contact Lens Technician |
| Costume & Make-Up | Colin Jamison | Hairstylist |
| Art | Neil Morrill | Sculptor |
| Costume & Make-Up | Shaunna Harrison | Makeup Artist |
| Crew | Michael Solinger | Post Production Supervisor |
| Directing | Matthew Sharp | Second Assistant Director |
| Art | Rob Bean | Sculptor |
| Costume & Make-Up | Janeen Schreyer | Makeup Designer |
| Costume & Make-Up | Lisa Tomblin | Hairstylist |
| Production | Terry Bamber | Production Manager |
| Production | Peter Heslop | Unit Production Manager |
| Production | Jacob Peratrovich | Assistant Unit Manager |
| Directing | Simon Crane | Second Unit Director |
| Art | Dominic Ackland-Snow | Supervising Carpenter |
| Art | Anthony Caron-Delion | Assistant Art Director |
| Production | Shelly Clippard | Associate Producer |
| Costume & Make-Up | Frances Hannon | Makeup Department Head |
| Directing | Pierros Andrakakos | Second Second Assistant Director |
| Directing | Cliff Lanning | First Assistant Director |
| Art | Christopher Arnold | Set Dresser |
| Art | John Fenner | Art Direction |
| Costume & Make-Up | Jan Jamison | Hairstylist |
| Costume & Make-Up | Belinda Parish | Makeup Artist |
| Costume & Make-Up | Jemma Scott-Knox-Gore | Contact Lens Technician |
| Production | Cindy Rodkin | Production Supervisor |
| Directing | Rob Burgess | Third Assistant Director |
| Directing | Ben Lanning | Third Assistant Director |
| Directing | Matthew Tang | First Assistant Director |
| Directing | Iain Lawrence | Assistant Director |
| Art | Silver Cheung | Art Direction |
| Production | Erica Bensly | Production Manager |
| Directing | Josephine Chan | Second Assistant Director |
| Directing | Tony Rimwah | Third Assistant Director |
| Costume & Make-Up | Tracey Lee | Makeup Artist |
| Directing | Thomas Chow Wai-Kwan | First Assistant Director |
| Directing | Terry Madden | First Assistant Director |
| Directing | Bob Nyanja | Third Assistant Director |
| Art | Mark Buck | Other |
| Art | Andrew David Clark | Graphic Designer |
| Art | Chris Clarke | Props |
| Art | Dennis Bosher | Art Direction |
| Art | John C. Hill | Art Direction |
| Production | Holly Goline | Associate Producer |
| Costume & Make-Up | Suzanne Belcher | Assistant Makeup Artist |
| Art | Frank Walsh | Art Direction |
| Production | Jeremy Johns | Production Manager |
| Production | Tim Lewis | Unit Manager |
| Production | Jenny Panoutsopoulos | Production Manager |
| Production | Johnny Wang Yin-Ming | Production Supervisor |
| Directing | Amy Gilliam | Assistant Director |
| Directing | Barbara Efthymiou Harris | Third Assistant Director |
| Directing | Martin Krauka | Second Second Assistant Director |
| Directing | Terence Madden | Third Assistant Director |
| Sound | Steve Boeddeker | Supervising Sound Editor |
| Art | Christopher Arnold | Props |
| Art | Rob Bliss | Conceptual Illustrator |
| Costume & Make-Up | Belinda Hodgson | Makeup Artist |
| Directing | Toby Hefferman | Second Assistant Director |
| Art | Andrew Barnden | Storyboard Artist |
| Sound | John Hughes | Sound |
| Sound | Peter Afterman | Music Supervisor |
| Visual Effects | Chris Corbould | Special Effects Supervisor |
| Visual Effects | Steven Begg | Visual Effects Supervisor |
| Crew | Simon Crane | Stunt Coordinator |
| Costume & Make-Up | Lindy Hemming | Costume Designer |
| Production | Kirk M. Petruccelli | Production Designer |
| Visual Effects | Ferran Domenech | Character Modelling Supervisor |
| Visual Effects | Ben Shepherd | Effects Supervisor |
