When a professor develops a vaccine that eliminates human allergies to dogs, he unwittingly upsets the fragile balance of power between cats and dogs and touches off an epic battle for pet supremacy. The fur flies as the feline faction, led by Mr. Tinkles, squares off against wide-eyed puppy Lou and his canine cohorts.
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| Sound | Mark A. Mangini | Supervising Dialogue Editor |
| Production | Chris Bender | Executive Producer |
| Production | Bruce Berman | Executive Producer |
| Sound | John Debney | Original Music Composer |
| Art | James D. Bissell | Production Design |
| Camera | Julio Macat | Director of Photography |
| Production | J.C. Spink | Executive Producer |
| Production | Craig Perry | Producer |
| Production | Warren Zide | Producer |
| Production | Andrew Lazar | Producer |
| Editing | Michael A. Stevenson | Editor |
| Writing | Glenn Ficarra | Screenplay |
| Writing | John Requa | Screenplay |
| Costume & Make-Up | Tish Monaghan | Costume Design |
| Directing | Lawrence Guterman | Director |
| Production | Christopher DeFaria | Producer |
| Editing | Rick Finney | Editor |
| Crew | J.J. Makaro | Stunt Coordinator |
| Writing | Bob Camp | Storyboard |
| Visual Effects | Craig Barron | Visual Effects Supervisor |
| Visual Effects | Eric Oliver | Animation |
| Visual Effects | John Slattery | Digital Compositor |
