In San Francisco de Macorís, Genaro, Chelo, and Carlitos work at a chocolate factory while Giuseppe prepares to manage a hotel abroad. After a chaotic series of incidents at the factory, Carlitos wins a safari trip to Africa and chooses Genaro and Chelo as his companions. Their journey unexpectedly leads them into Giuseppe’s professional world at a luxury resort in Nairobi. During a safari, disaster strikes when they trigger a stampede and become separated in the savannah. Each is taken in by a different tribe and mistaken for a prophesied leader, just as a tribal war over land and diamond mines is about to begin. Giuseppe and Goberto try to stop the conflict, but Giuseppe is captured for a ritual. In the end, the trio prevents the war, saves Giuseppe, and returns home, only to discover they have become owners of fortunes worth 100 million dollars each.
Is Sanky Panky 4: The Safari on Netflix? Unfortunately the movie Sanky Panky 4: The Safari is not yet available on Netflix.
| Directing | Elias Acosta | Director |
| Writing | Elias Acosta | Writer |
| Production | Elias Acosta | Producer |
| Production | Rafael Taveras | Producer |
| Production | Franklin Romero Jr. | Executive Producer |