Sheena's parents are killed while on Safari. She is raised by the mystical witch woman of an African tribe. When her foster mother is framed for the murder of a political leader, Sheena and a newsman, Vic Casey, are forced to flee while pursued by the mercenaries hired by the real killer, who hopes to assume power. Sheena's ability to talk to the animals and knowledge of jungle lore give them a chance against the high tech weapons of the mercenaries.
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| Directing | John Guillermin | Director |
| Production | Paul Aratow | Producer |
| Writing | Lorenzo Semple Jr. | Screenplay |
| Writing | David Newman | Screenplay |
| Camera | Pasqualino De Santis | Director of Photography |
| Editing | Ray Lovejoy | Editor |
| Sound | Richard Hartley | Original Music Composer |
| Sound | Richard Hartley | Conductor |
| Art | Peter Murton | Production Design |
| Production | Yoram Ben-Ami | Executive Producer |
| Writing | Leslie Stevens | Story |
| Writing | David Newman | Story |
| Production | Jane Feinberg | Casting |
| Production | Mike Fenton | Casting |
| Production | Maggie Cartier | Casting |
| Costume & Make-Up | Annalisa Nasalli-Rocca | Costume Design |
| Production | Christian Ferry | Associate Producer |
| Production | Alan Rinzler | Associate Producer |
| Art | Malcolm Middleton | Art Direction |
| Directing | Patrick Clayton | First Assistant Director |
| Production | Danny ben Menahem | Unit Manager |
| Sound | Brian Simmons | Sound Mixer |
| Production | Peter Cotton | Location Manager |
| Production | Matthew Kipoin | Location Manager |
| Directing | Caroline Sax | Continuity |
| Camera | Jimmy Turrell | Camera Operator |
| Camera | Cesare Allione | Camera Operator |
| Camera | Aldo Colanzi | Key Grip |
| Art | Ian Watson | Set Decoration |
| Art | John Wood | Assistant Art Director |
| Directing | Callum McDougall | Third Assistant Director |
| Directing | Bill Mizel | Second Assistant Director |
| Directing | Tom Mwangi | Assistant Director |
| Costume & Make-Up | Stefano Fava | Makeup Supervisor |
| Costume & Make-Up | Christine Allsopp | Makeup Artist |
| Costume & Make-Up | Gloria Fava | Makeup Artist |
| Costume & Make-Up | Bernard Gough | Hairdresser |
| Art | Arthur Wicks | Property Master |
| Sound | Gary Weir | Boom Operator |
| Production | Liz Kerry | Production Coordinator |
| Production | Jak King | Production Accountant |
| Visual Effects | Peter Hutchinson | Special Effects Supervisor |
| Lighting | Laurie Shane | Gaffer |
| Lighting | Fiorangelo Plocco | Gaffer |
| Lighting | Luciano Leoni | Gaffer |
| Crew | Robert Nugent | Special Effects Coordinator |
| Crew | Roy Scammell | Stunt Coordinator |
| Camera | David Farrell | Still Photographer |
| Production | Joy Helman | Publicist |
| Crew | Brian Hathaway | Transportation Coordinator |
| Directing | Jack Couffer | Second Unit Director |
| Sound | Don Sharpe | Supervising Sound Effects Editor |
| Sound | Michael Clifford | Music Editor |
| Sound | Derek Trigg | Sound Editor |
| Sound | Paul Smith | Sound Editor |
| Editing | Phil Sanderson | Assistant Editor |
| Sound | David Sharpe | Assistant Sound Editor |
| Sound | Pat Gilbert | Assistant Sound Editor |
| Sound | Sarah Thomas | Assistant Sound Editor |
| Sound | Paula Connor | Assistant Sound Editor |
| Crew | Mike Potter | Stunts |
| Camera | Franco Bruni | Camera Operator |
| Crew | Norman Howell | Utility Stunts |
| Crew | Cheryl Harris | Stunts |
| Crew | Terry Forrestal | Stunts |
| Crew | Dominique Julienne | Stunts |
| Crew | Sadie Eden | Stunts |
| Crew | Tracey Eddon | Stunts |
| Crew | Billy Bates | Stunts |
| Crew | Joëlle Baland | Stunts |
| Crew | Brian Bowes | Stunts |
| Crew | Rémy Julienne | Stunts |
| Crew | Jean-Claude Lagniez | Stunts |
| Crew | Malcolm Weaver | Stunts |
| Crew | Jason White | Stunts |
