A philosophical burlesque, Human Nature follows the ups and downs of an obsessive scientist, a female naturalist, and the man they discover, born and raised in the wild. As scientist Nathan trains the wild man, Puff, in the ways of the world - starting with table manners - Nathan's lover Lila fights to preserve the man's simian past, which represents a freedom enviable to most.
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| Directing | Michel Gondry | Director |
| Camera | Tim Maurice-Jones | Director of Photography |
| Editing | Russell Icke | Editor |
| Production | Jeanne McCarthy | Casting |
| Production | Charlie Kaufman | Producer |
| Production | Anthony Bregman | Producer |
| Production | Spike Jonze | Producer |
| Art | K.K. Barrett | Production Design |
| Costume & Make-Up | Nancy Steiner | Costume Design |
| Art | Gene Serdena | Set Decoration |
| Production | Ted Hope | Producer |
| Sound | Graeme Revell | Original Music Composer |
| Art | Peter Andrus | Art Direction |
| Visual Effects | Pierre Buffin | Visual Effects Supervisor |
| Sound | David Bach | Sound Re-Recording Mixer |
| Sound | Joe Barnett | Sound Re-Recording Mixer |
| Sound | John Reese | Sound Editor |
| Sound | John Reese | Sound Re-Recording Mixer |
| Production | Julie Fong | Co-Producer |
| Writing | Charlie Kaufman | Writer |
| Crew | Joni Avery | Stunt Double |
| Crew | Al Goto | Stunts |
| Crew | Tim Rigby | Stunt Double |
